Gold-catalyzed functionalization of unactivated C(sp 3)-H bonds by hydride transfer facilitated by alkynylspirocyclopropanes
- Barluenga, J. 1
- Sigüeiro, R. 1
- Vicente, R. 1
- Ballesteros, A. 1
- Tomás, M. 1
- Rodríguez, M.A. 2
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1
Universidad de Oviedo
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2
Universidad de La Rioja
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ISSN: 1433-7851
Datum der Publikation: 2012
Ausgabe: 51
Nummer: 41
Seiten: 10377-10381
Art: Artikel
Andere Publikationen in: Angewandte Chemie International
Projekte im Zusammenhang
Zusammenfassung
A Golden Gate: Alkynylspirocyclopropanes served as a template for the development of gold-catalyzed hydride transfer from unactivated C(sp 3)-H bonds to electronically neutral alkynes. A variety of interesting carbocyclic structures can be accessed selectively with the appropriate choice of the reaction conditions. Mechanistic studies support a sequential gold-catalyzed cleavage of C-H and C-C bonds. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.