Serological diagnosis of neurobrucelosis

  1. Sánchez-Sousa, Aurora .
  2. Torres, C.
  3. Campello, M.G.
  4. Garcia, C.
  5. Parras, Francisco .
  6. Cercenado, E.
  7. Baquero, F.
  1. 1 Hospital Ramón y Cajal
    info

    Hospital Ramón y Cajal

    Madrid, España

    ROR https://ror.org/050eq1942

Revista:
Journal of Clinical Pathology - Clinical Molecular Pathology

ISSN: 0021-9746

Año de publicación: 1990

Volumen: 43

Número: 1

Páginas: 79-81

Tipo: Artículo

PMID: 2312754 SCOPUS: 2-s2.0-0025141876 GOOGLE SCHOLAR

Otras publicaciones en: Journal of Clinical Pathology - Clinical Molecular Pathology

Resumen

The presence of antibodies was determined in the serum and cerebrospinal fluid in six patients with neurobrucellosis using the Rose Bengal test, the microdilution agglutination test, and the Coombs' test. Four of the patients were followed up for more than three months. The Rose Bengal test and the microagglutination test were positive in cerebrospinal fluid in five of the six cases at some stage. The Coombs' test was positive in cerebrospinal fluid in every patient and in one was the only positive serological test. Cerebrospinal fluid positivity is not excluded by low titres or negative results of antibodies in the serum for any of the three methods. A Coombs' test or some equivalent must always be made on the cerebrospinal fluid to diagnose neurobrucellosis.