Publicaciones en las que colabora con Gonçalo Bernardes (47)

2023

  1. Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions

    Journal of the American Chemical Society, Vol. 145, Núm. 19, pp. 10790-10799

  2. Merging the Isonitrile-Tetrazine (4+1) Cycloaddition and the Ugi Four-Component Reaction into a Single Multicomponent Process

    Angewandte Chemie - International Edition, Vol. 62, Núm. 44

  3. Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules

    ACS Central Science, Vol. 9, Núm. 5, pp. 892-904

2022

  1. Controlled In-Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging

    Angewandte Chemie - International Edition, Vol. 61, Núm. 8

  2. Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination

    Nature Chemistry, Vol. 14, Núm. 7, pp. 754-765

  3. Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents

    Journal of the American Chemical Society, Vol. 144, Núm. 23, pp. 10396-10406

  4. Selective Inhibition of Bruton’s Tyrosine Kinase by a Designed Covalent Ligand Leads to Potent Therapeutic Efficacy in Blood Cancers Relative to Clinically Used Inhibitors

    ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1156-1168

  5. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294

2021

  1. Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems

    Journal of the American Chemical Society, Vol. 143, Núm. 40, pp. 16401-16410

  2. Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression

    ACS Central Science, Vol. 7, Núm. 5, pp. 868-881

  3. Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions

    Bioconjugate Chemistry, Vol. 32, Núm. 8, pp. 1812-1822

  4. Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

    Organic Letters, Vol. 23, Núm. 21, pp. 8580-8584

  5. Dichloro Butenediamides as Irreversible Site-Selective Protein Conjugation Reagent

    Angewandte Chemie - International Edition, Vol. 60, Núm. 44, pp. 23750-23755

2020

  1. Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects

    Cell Metabolism, Vol. 31, Núm. 6, pp. 1120-1135.e7

  2. Precise Installation of Diazo-Tagged Side-Chains on Proteins to Enable in Vitro and In-Cell Site-Specific Labeling

    Bioconjugate Chemistry, Vol. 31, Núm. 6, pp. 1604-1610

  3. Precise protein conjugation technology for the construction of homogenous glycovaccines

    Drug Discovery Today: Technologies, Vol. 38, pp. 69-75

  4. Sequential dual site-selective protein labelling enabled by lysine modification

    Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22

  5. Stable Pyrrole-Linked Bioconjugates through Tetrazine-Triggered Azanorbornadiene Fragmentation

    Angewandte Chemie - International Edition, Vol. 59, Núm. 15, pp. 6196-6200

  6. Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

    RSC Chemical Biology, Vol. 1, Núm. 4, pp. 251-262

  7. Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

    Chemical Communications, Vol. 56, Núm. 96, pp. 15137-15140