PROYECTOS I+D
Proyecto CTQ2012-36365 RIDGE
Diseño racional de glicopéptidos con aplicaciones en Química Biológica
date_range
Duración del 01 de enero de 2013 al 31 de diciembre de 2015
(36 meses)
euro
182.520,00 EUR
De ámbito Nacional.
Investigadores/as
Publicaciones relacionadas con el proyecto (17)
Mostrar por anualidadTesis
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New insights into molecular recognition of epitopes related to MUC1 human mucin by lectins
2015
Madariaga Merino, David
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Síntesis y análisis conformacional de glicopéptidos que incorporan ß-glucosa y a-N-acetilgalactosamina
2014
Somovilla Busto, Víctor Jesús
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Diseño racional de derivados de mucina como candidatos a vacunas contra el cáncer
2013
Martínez Sáez, Nuria
Artículo
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Detection of tumor-associated glycopeptides by Lectins: The peptide context modulates carbohydrate recognition
2015
ACS chemical biology
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Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β2,2-amino acids
2015
Chemistry - A European Journal
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Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation
2015
Nature Communications
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Synthesis of Mixed α/β2,2-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates
2015
Organic Letters
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S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-tn antigen mimic
2014
Journal of the American Chemical Society
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Conformational preferences of Chiral acyclic homooligomeric β2,2-Peptides
2014
Current Topics in Medicinal Chemistry
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Influence of amino acid stereocenters on the formation of bicyclic N, O -acetals
2014
Journal of Organic Chemistry
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Serine versus Threonine Glycosylation witha-O-GalNAc: Unexpected Selectivity in Their Molecular Recognition with Lectins
2014
Chemistry - A European Journal
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Conformational analysis of peptides and glycopeptides derived from the consensus sequence for β-O-glucosylation
2014
Current Topics in Medicinal Chemistry
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Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase 2
2014
Angewandte Chemie International
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Chemoselectivity control in the reactions of 1,2-cyclic sulfamidates with amines
2013
Chemistry - A European Journal
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Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose
2013
Carbohydrate Research
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Ring-rearrangement metathesis of 7-azanorbornenes as an entry to 1-azabicyclo[n.3.0]alkenones
2013
European Journal of Organic Chemistry
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A double diastereoselective michael-type addition as an entry to conformationally restricted Tn antigen mimics
2013
Journal of Organic Chemistry