Multiple solid phase microextraction. Theory and applications
- Tena, M.T. 1
- Carrillo, J.D. 1
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1
Universidad de La Rioja
info
ISSN: 0165-9936
Año de publicación: 2007
Volumen: 26
Número: 3
Páginas: 206-214
Tipo: Artículo
Otras publicaciones en: TrAC. Trends in Analytical Chemistry Regular ed.
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Resumen
Multiple solid-phase microextraction (MSPME) is a stepped procedure suitable for avoiding matrix-effect errors in quantitative analyses of complex matrix samples by SPME. It is based on calculating the amount of analyte corresponding to complete extraction using the peak areas of a few consecutive extractions from the same sample. This article reviews the state of the art in MSPME, including theory and applications. It also includes a debate on calculating the limits of detection and quantification, and the use of this methodology to determine fiber-sample distribution constant. © 2007 Elsevier Ltd. All rights reserved.