Multiple solid phase microextraction. Theory and applications

  1. Tena, M.T. 1
  2. Carrillo, J.D. 1
  1. 1 Universidad de La Rioja

    Universidad de La Rioja

    Logroño, España

    GRID grid.119021.a

TrAC. Trends in Analytical Chemistry Regular ed.

ISSN: 0165-9936

Year of publication: 2007

Volume: 26

Issue: 3

Pages: 206-214

Type: Article

Export: RIS
DOI: 10.1016/j.trac.2007.01.008 SCOPUS: 2-s2.0-33847318326 WoS: 000245499300017 GOOGLE SCHOLAR


Cited by

  • Scopus Cited by: 57 (12-06-2021)

Journal Citation Reports

  • Year 2007
  • Journal Impact Factor: 5.827
  • Best Quartile: Q1
  • Area: CHEMISTRY, ANALYTICAL Quartile: Q1 Rank in area: 1/70 (Ranking edition: SCIE)

SCImago Journal Rank

  • Year 2007
  • SJR Journal Impact: 2.172
  • Best Quartile: Q1
  • Area: Analytical Chemistry Quartile: Q1 Rank in area: 6/89
  • Area: Environmental Chemistry Quartile: Q1 Rank in area: 5/93
  • Area: Spectroscopy Quartile: Q1 Rank in area: 4/58


Multiple solid-phase microextraction (MSPME) is a stepped procedure suitable for avoiding matrix-effect errors in quantitative analyses of complex matrix samples by SPME. It is based on calculating the amount of analyte corresponding to complete extraction using the peak areas of a few consecutive extractions from the same sample. This article reviews the state of the art in MSPME, including theory and applications. It also includes a debate on calculating the limits of detection and quantification, and the use of this methodology to determine fiber-sample distribution constant. © 2007 Elsevier Ltd. All rights reserved.