Regioselective Ring-Opening Metathesis-Cross Metathesis of Bridgehead-Substituted 7-Azanorbornene

  1. Carreras, J. 1
  2. Avenoza, A. 1
  3. Busto, J.H. 1
  4. Peregrina, J.M. 1
  1. 1 Universidad de La Rioja
    info

    Universidad de La Rioja

    Logroño, España

    ROR https://ror.org/0553yr311

Zeitschrift:
Organic Letters

ISSN: 1523-7060

Datum der Publikation: 2007

Ausgabe: 9

Nummer: 7

Seiten: 1235-1238

Art: Artikel

DOI: 10.1021/OL0631051 SCOPUS: 2-s2.0-34147121488 WoS: WOS:000245084300016 GOOGLE SCHOLAR

Andere Publikationen in: Organic Letters

Projekte im Zusammenhang

Síntesis y análisis conformacional de o-glicoaminoacidos y o-glicopeptidos modelo de interés biológico

2006/00086/001

Zusammenfassung

Figure presented In this paper we describe a highly regioselective ring-opening metathesis-cross metathesis (ROM-CM) process between methyl N-Boc-7-azabicyclo[2.2.1]hept-2-en-1-carboxylate, a bridgehead-substituted 7-azanorbornene system, and electron-poor olefins. The reaction opens the way to the synthesis of interesting α-amino diacids and pyrrolizinone derivatives that incorporate quaternary stereocenters. © 2007 American Chemical Society.